Biocatalysis -
from Discovery to Application

We have a passion for sustainable processes and enzymes, bringing us a step closer to green synthetic strategies.

Research Highlights

ACS Catalysis (2025): “Hybrid Catalytic Systems: Integrating Biocatalysis in the Chemical Space”

September 8, 2025

ACS Omega (2025): “Covalent immobilization of different enzymes on hydroxyapatite, an alternative green support”

September 8, 2025

Group News

Aare Böötle 2025

August 21, 2025

Twitter

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Projects

Enzyme Toolbox

We have introduced many enzymes in our toolbox over the years (and we always look for more!) to make our chemistry more and more versatile.

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Flow Biocatalysis

We combine different enzymes, those that offer optimal characteristics for our chemistry, in continuous artificial biocatalytic pathways.

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Enzyme immobilization

Enzyme stability can be greatly enhanced if the biocatalyst is anchored to a support. We develop novel strategies for enzyme immobilization.

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Chemo-enzymatic Processes

Flow equipment and compartmentalisation of reaction steps offer an exceptional opportunity to integrate enzymes in organic syntheses.

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Publications

Papers

Collection of the group research and review articles to date

Books & Chapters

Making a difference in the education of the next generation of scientists

Patents

Our discoveries with IP status in the field of biocatalysis and chemistry

Funding

Roche

Francesca Paradisi

Professor of Sustainable Pharmaceutical Chemistry

Department of Chemistry, Biochemistry and Pharmaceutical Sciences
University of Bern

Freiestrasse 3, 3012 Bern, Switzerland

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Biocatalysis -from Discovery to Application