Biocatalysis -
from Discovery to Application

We have a passion for sustainable processes and enzymes, bringing us a step closer to green synthetic strategies.

Research Highlights

RSC Sust. (2024): “Membrane-immobilized transaminases for the synthesis of enantiopure amines”

November 10, 2024

Helv. Chim. Acta (2024): “Cost-Effective and Sustainable Scale-Up of Short-Chain Primary Amines”

November 10, 2024

Group News

Dr. Pablo Díaz-Kruik!

January 11, 2025

And it’s a wrap for 2024!

December 20, 2024

Twitter

ParadisiResearch Follow

Discovery Evolution Application #biocatalysis #enzymes #flow #enzymeimmobilization @DCBunibern

Avatar ParadisiResearch @paradisireslab ·

10 Jan

What an amazing day! Congratulations to @DiazKruikP on becoming the latest dr in the house! Many thanks to @NoelGroupUvA and @albrecht_lab for the work as examiner and chair!

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Projects

Enzyme Toolbox

We have introduced many enzymes in our toolbox over the years (and we always look for more!) to make our chemistry more and more versatile.

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Flow Biocatalysis

We combine different enzymes, those that offer optimal characteristics for our chemistry, in continuous artificial biocatalytic pathways.

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Enzyme immobilization

Enzyme stability can be greatly enhanced if the biocatalyst is anchored to a support. We develop novel strategies for enzyme immobilization.

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Integrated Chemo-enzymatic Processes

Flow equipment and compartmentalisation of reaction steps offer an exceptional opportunity to integrate enzymes in organic syntheses.

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Publications

Papers

Collection of the group research and review articles to date

Books & Chapters

Making a difference in the education of the next generation of scientists

Patents

Our discoveries with IP status in the field of biocatalysis and chemistry

Funding

Roche

Francesca Paradisi

Professor of Sustainable Pharmaceutical Chemistry

Department of Chemistry, Biochemistry and Pharmaceutical Sciences
University of Bern

Freiestrasse 3, 3012 Bern, Switzerland

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Biocatalysis -from Discovery to Application