Biocatalysis -
from Discovery to Application

We have a passion for sustainable processes and enzymes, bringing us a step closer to green synthetic strategies.

Research Highlights

ACS Sus Chem Eng (2025): “Biocatalytic Reduction of Six-membered Ring Heterocyclic Imines in Continuous Flow”

March 25, 2025

Chem & Bio Eng (2025): “Crystallization-assisted asymmetric synthesis of enantiopure amines using membrane-immobilized transaminase”

March 18, 2025

Group News

Biotrans 2025

July 11, 2025

CSC 2025 Ottawa

June 23, 2025

Twitter

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Projects

Enzyme Toolbox

We have introduced many enzymes in our toolbox over the years (and we always look for more!) to make our chemistry more and more versatile.

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Flow Biocatalysis

We combine different enzymes, those that offer optimal characteristics for our chemistry, in continuous artificial biocatalytic pathways.

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Enzyme immobilization

Enzyme stability can be greatly enhanced if the biocatalyst is anchored to a support. We develop novel strategies for enzyme immobilization.

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Chemo-enzymatic Processes

Flow equipment and compartmentalisation of reaction steps offer an exceptional opportunity to integrate enzymes in organic syntheses.

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Publications

Papers

Collection of the group research and review articles to date

Books & Chapters

Making a difference in the education of the next generation of scientists

Patents

Our discoveries with IP status in the field of biocatalysis and chemistry

Funding

Roche

Francesca Paradisi

Professor of Sustainable Pharmaceutical Chemistry

Department of Chemistry, Biochemistry and Pharmaceutical Sciences
University of Bern

Freiestrasse 3, 3012 Bern, Switzerland

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Biocatalysis -from Discovery to Application