Well done to Anita! Her work finally rewarded! This paper was the result of our collaborative work with Prof. Gallagher at Wake Forest University in North Carolina and the major stabilising effect of incorporating our non natural cyclic amino acid into the Angiotensin sequence, without loosing its anti proliferative properties is a significant step forward in bringing this therapeutic peptide to the market. (doi:10.1007/s00726-017-2471-9)