Advanced Synthesis and Catalysis (2026): “Biocatalytic Application of Goodfellowiella coeruleoviolaceaImine Reductase: Enantioselective Synthesis of Cyclic Secondary Amines in Deep Eutectic Solvent-Based Media”

The development of sustainable strategies for accessing optically pure amines is essential for pharmaceutical and fine-chemical manufacturing. Here, we report the characterization of a newly identified imine reductase from Goodfellowiella coeruleoviolacea (GcIRED) and its application to the asymmetric reduction of cyclic imines in deep eutectic solvent based media. GcIRED displayed excellent catalytic performance in choline […]