ChemBioChem (2022): “Fusion of Formate Dehydrogenase and Alanine Dehydrogenase as an Amino Donor Regenerating System Coupled to Transaminases”
Another paper from Valentina with the contribution of our master student Sopha and Ana. Abstract: A fusion protein combining alanine dehydrogenase and formate dehydrogenase has been successfully produced as a bifunctional enzyme. Two different genetic designs by swapping the position of both protein domains were developed, but one construct showed up to 2.5-fold higher enzymatic activity than […]
Green Chemistry (2020): “Cell-free biocatalytic synthesis of pipecolic acid: a dual strategy approach and process intensification in flow”
This work was supported by the Wellcome Prime Award Fran received in 2018 through the University of Nottingham. This grant funded Ana for several month as a Post Doc in Nottingham and together with David they worked on a very nice system to produce pipe colic acid (high value molecule) from simple lysine. Liam was a fourth […]