Appl Microbiol Biotechnol (2020): “Engineering novel S-glycosidase activity into extremo-adapted β-glucosidase by rational design”
This paper presents Nourah’s work on how strategic site directed mutagenesis has been successfully applied to shift substrate preference in glycosyl hydrolases. The mutant enzyme is now able to work with thio-glycosides which are found in several plants and have shown both antimicrobial and anticancer activity. In fact the identified positions could be used also […]
Green Chemistry (2019): “Flow-based enzymatic synthesis of melatonin and other high value tryptamine derivatives: a five-minute intensified process”
To increase the uptake of biocatalytic processes by industry, it is essential to demonstrate the reliability of enzyme-based methodologies directly applied to the production of high value products. Here, an ultra-efficient, and sustainable enzymatic platform for the multi-gram synthesis of melatonin (and analogues) was developed. The fully-automated process integrates biocatalysis and flow chemistry, maximizes the […]
Nature Catalysis (2018): Self-sustaining closed-loop multienzyme-mediated conversion of amines into alcohols in continuous reactions
Massive congratulation to Martina for this achievement! The paper summarises an outstanding amount of work with very clever applications. Find the paper here Or you can access a read only version here Related Posts