A. I. Benítez-Mateos, F. Paradisi “Sustainable (flow)synthesis of antiviral and anticancer nucleosides by a novel purine nucleoside phosphorylase reversibly immobilized” ChemSusChem 2022, 15, e202102030 (10.1002/cssc.202102030)

V. Marchini, A. I. Benítez-Mateos, D. Roura Padrosa, F. Paradisi “Chimeric fusion of glutamate dehydrogenase and formate dehydrogenase yields a bifunctional efficient biocatalyst for the continuous removal of ammoniaFrontiers in Catalysis 2021, 1, art 790461 (10.3389/fctls.2021.790461)

C. M. Heckmann, F. Paradisi “GPhos ligand enables the production of chiral N-arylamines in a telescoped transaminase–Buchwald-Hartwig amination cascade in the presence of excess amine donor” Chemistry- A European Journal 2021, 27, 16616-16620(10.1002/chem.202103472) (Included in the Hot Topic: Biocatalysis)

K. Lenzen, M. Planchestainer, I. Feller, D. Roura Padrosa, F. Paradisi, M. Albrecht “Minimalistic peptidic scaffolds harbouring an artificial carbene-containing amino acid modulate reductase activityChemical Communication 2021, 57, 9068 – 9071 (10.1039/D1CC03158A)

A. I. Benítez-Mateos, S. Bertella, J. Behaghel de Bueren, J. Luterbacher, F. Paradisi “Dual revalorization of lignin through its use as a versatile and renewable matrix for enzyme immobilization and (flow)bioprocess engineeringChemSusChem 2021, 14, 3198-3207 (doi: 10.1002/cssc.202100926)(Selected as the #ChemSusChemReaders Choice August 2021)

U. Montanari, D. Cocchi, T. M. Brugo, A. Pollicino, V. Taresco, M. Romero-Fernandez, F. Paradisi, A. Zucchelli, S. Howdle, C. Gualandi “Functionalizable epoxide-rich electrospun fiber based on renewable terpene for multi-purpose applicationsPolymers 2021, 13, 1804 (doi: 10.3390/polym13111804)

M. Romero-Fernandez, F. Paradisi “Biocatalytic access to betazole by one-pot multienzymatic system in continuous flowGreen Chemistry 2021, 23, 4595-4603 (doi: 10.1039/D1GC01095F)

D. Roura Padrosa, Z. Nissar, F. Paradisi “Efficient amino donor recycling in amination reactions: development of a new alanine dehydrogenase in continuous flow and dialysis membrane reactorsCatalysts 2021, 11, 520 (doi: 10.3390/catal11040520)

C. M. Heckmann, B. Dominiguez, F. Paradisi “Enantio-complementary continuous-flow synthesis of 2-aminobutane using covalently immobilized transaminases” ACS Sustainable Chemistry and Engineering 2021, 9, 4122-4129 (doi: 10.1021/acssuschemeng.0c09075)

L. Delgado, C. M. Heckmann, L. J. Gourlay, F. Paradisi “Producing natural vanilla extract from green vanilla beans using a β-glucosidase from Alicyclobacillus acidiphilusJournal of Biotechnology 2021, 329, 21-28 (doi:10.1016/j.jbiotec.2021.01.017)

D. Roura Padrosa, V. Marchini, F. Paradisi “CapiPy: python-based GUI-application to assist in protein immobilizationBioinformatics 2021, btab030 (doi: 10.1093/bioinformatics/btab030)

L. Delgado, C. M. Heckmann, F. Di Pisa, L. J. Gourlay, F. Paradisi “Release of soybean isoflavones using a β-Glucosidase from Alicyclobacillus herbariusChemBioChem 2021, 22, 1223-1231 (doi: 10.1002/cbic.202000688) 



M. L. Contente, D. Roura Padrosa, F. Molinari, F. Paradisi “A strategic Ser/Cys exchange in the catalytic triad unlocks an acyltransferase-mediated synthesis of thioesters and tertiary amidesNature Catalysis 2020, 3, 1020-1026 (doi: 10.1038/s41929-020-00539-0) 

E. Hegarty, F. Paradisi “Implementation of biocatalysis in continuous flow for the synthesis of small cyclic amines” CHIMIA 2020, 74, 890-894 (doi:10.2533/chimia.2020.890)

M. L. Contente, N. Fiore, P. Cannazza, D. Roura Padrosa, F. Molinari, L. Gourlay, F. Paradisi “Uncommon overoxidative catalytic activity in a new halo-tolerant alcohol dehydrogenaseChemCatChem 2020, 125679-5685 (doi: 10.1002/cctc.202001112 

D. Roura Padrosa, A. I. Benítez-Mateos, L. Calvey, F. Paradisi “Cell-free biocatalytic synthesis of pipecolic acid: a dual strategy approach and process intensification in flow” Green Chemistry 2020, 22, 5310- 5316 (doi:10.1039/D0GC01817A) (Selected as one of the 2020 HOT Green Chemistry article)

M. Planchestainer, J. McMaster, C. Schulz, F. Paradisi, M. Albrecht “Carbene-induced rescue of catalytic activity in deactivated Nitrite Reductase mutantChemistry: a European Journal 2020, 26, 15206-15211 (doi: 10.1002/chem.202002444) 

C. Heckmann, L. Gourlay, B. Dominiguez, F. Paradisi “An (R)-Selective Transaminase from Thermomyces stellatus: Stabilizing the Tetrameric FormFrontiers in Bioengineering and Biotechnology 2020, 8, art 707 (doi: 10.3389/fbioe.2020.00707)

L. Delgado, M. Parker, I. Fisk, F. Paradisi “Performance of the extremophilic enzyme BglA in the hydrolysis of two aroma glucosides in a range of model and real wines and grape juices” Food Chemistry 2020, 323, 126825 (DOI: 10.1016/j.foodchem.2020.126825)

N. Almulhim, N. R. Moody, F. Paradisi “Engineering novel S-glycosidase activity into extremo-adapted β-glucosidase by rational design” Applied Microbiology and Biotechnology 2020, 104, 4407-4415 (DOI: 10.1007/s00253-020-10582-3)

M. L. Contente, L. Tamborini, F. Molinari, F. Paradisi “Aromas flow: Eco-friendly, continuous, and scalable preparation of flavour estersJournal of Flow Chemistry 2020, 10, 235-240 (DOI: 10.1007/s41981-019-00063-8



D. Roura Padrosa, R. Alaux, P. Smith, I. Dreveny, F. López-Gallego, F. Paradisi “Enhancing PLP-binding capacity of class-III ω-transaminases by single residue substitutionFrontiers in Bioengineering and Biotechnology 2019, 7, art 282 (DOI:10.3389/fbioe.2019.00282

M. L. Contente, F. Paradisi Transaminase-catalyzed continous synthesis of biogenic aldehydesChemBioChem 2019, 20, 2830-2833 (DOI:10.1002/cbic.201900356) – (Selected for the Hot Topic: Biocatalysis collection)

M. L. Contente, S. Farris, L. Tamborini, F. Molinari, F. Paradisi “Flow-based enzymatic synthesis of melatonin and other high value tryptamine derivatives: a five-minute intensified process” Green Chemistry 2019, 21, 32633266 (DOI:10.1039/C9GC01374A) 

I. Chiarelli Perdomo, S. Gianolio, A. Pinto, D. Romano, M. L. Contente, F. Paradisi, F. Molinari “Efficient enzymatic preparation of flavor esters in water” Journal of Agricultural and Food Chemistry 2019, 67, 6517−6522 (DOI:10.1021/acs.jafc.9b01790

M. Planchestainer, E. Hegarty, C. Heckmann, L. Gourlay, F. Paradisi “Widely applicable background depletion step enables transaminase evolution through solid-phase screeningChemical Science 2019, 10, 5952 – 5958 (DOI: 10.1039/C8SC05712E) 

R. ul Haque, F. Paradisi, T. Allers “Haloferax volcanii as immobilised whole cell biocatalyst: new applications for halophilic systemsApplied Microbiology and Biotechnology 2019, 103, 38073817 (doi: 10.1007/s00253-019-09725-y)

D. Roura Padrosa, V. De Vitis, M. L. Contente, F. Molinari, F. Paradisi “Overcoming water insolubility in flow: enantioselective hydrolysis of Naproxen esterCatalysts 2019, 9, 32 (doi: 10.3390/catal9030232)

L. Josa-Culleré, A. S. K. Lahdenperä, A. Ribaucourt, G. T. Höfler, S. Gargiulo, Y. Liu, J. Xu, J. Cassidy, F. Paradisi, D. J. Opperman, F. Hollmann, C. E. Paul “Synthetic biomimetic coenzymes and alcohol dehydrogenases for asymmetric catalysisCatalysts 2019, 9, 207 (doi: 10.3390/catal9030207) 

A. Di Matteo, L. Federici, M. Masulli, E. Carletti, D. Santorelli, J. Cassidy, F. Paradisi, C. Di Ilio, N. Allocati “Structural characterization of the Xi class glutathione transferase from the haloalkaliphilic archaeon Natrialba magadii.” Frontiers in Microbiology 2019, 10, Art. No.: 9 (doi: 10.3389/fmicb.2019.00009 )



K. Guggenheim, L. Crawford, F. Paradisi, S. Wang, J. Siegel “b-Glucosidase Discovery and Design for the Degradation of OleuropeinACS Omega  2018, 3, 15754-15762 (doi: 10.1021/acsomega.8b02169)

B. Guidi, M. Plachestainer,  M. L. Contente, T. Laurenzi, I. Eberini, L. J. Gourlay, D. Romano, F. Paradisi, F. Molinari “Strategic single point mutation yields a solvent- and salt-stable transaminase from Virgibacillus sp. in soluble formScientific Reports 2018, 8, Art. No.: 16441(doi: 10.1038/s41598-018-34434-3)

M. L. Contente, A. Pinto, F. Molinari, F. Paradisi “Biocatalytic N‐Acylation of Amines in Water Using an Acyltransferase from Mycobacterium smegmatis” Advanced Synthesis & Catalysis 2018, 360, 4814-4819 (doi: 10.1002/adsc.201801061)

A. I. Benítez-Mateos, M. L. Contente, S. Velasco-Lozano, F. Paradisi, F. Lopez-Gallego “Self-sufficient flow-biocatalysis by co-immobilisation of pyridoxal 5´-phosphate and ω-transaminases onto porous carriersACS Sustainable Chemistry & Engineering 2018, 6, 13151-13159 (doi: 10.1021/acssuschemeng.8b02672)

M. Planchestainer, N. Ségaud, M. Shanmugam, J. McMaster, F. Paradisi, M. Albrecht “Carbene in cupredoxin protein scaffolds: replacement of a histidine ligand in the active site substantsubstantially alters copper redox propertiesAngewandte Chemie 2018, 57, 10677-10682 (doi:10.1002/anie.201807168)

C. Carucci, L. Bruen, V. Gascon Perez, F. Paradisi, E. Magner “Significant enhancement of structural stability of the hyperhalophilic ADH from Haloferax Volcanii via entrapment on metal organic framework support” Langmuir 2018, 34, 8274-8280  (doi:10.1021/acs.langmuir.8b01037) 

M. L. Contente, F. Paradisi “Self-sustaining closed-loop multienzyme-mediated conversion of amines into alcohols in continuous reactionsNature Catalysis 2018, 1, 452-459 (doi:10.1038/s41929-018-0082-9) (Highlighted in C&EN magazine – June 2018)

J. Cassidy, F. Paradisi “Haloquadratum walsbyi yields a versatile, NAD+/NADP+ dual affinity, thermostable, alcohol dehydrogenase (HwADH)” Molecular Biotechnology 2018, 60, 420-426 (doi:10.1007/s12033-018-0083-6)

M. Planchestainer, D. Roura Padrosa, M. L. Contente, F. Paradisi “Genetically Fused T4L Acts as a Shield in Covalent Enzyme Immobilisation Enhancing the Rescued Activity” Catalysts 2018, 8, 40 (doi:10.3390/catal8010040)



J. Cassidy, L. Bruen, E. Rosini, G. Molla, L. Pollegioni, F. Paradisi “Engineering substrate promiscuity in halophilic alcohol dehydrogenase (HvADH2) by in silico designPlosOne 2017, 12, e0187482 (doi: https://doi.org/10.1371/journal.pone.0187482)

D. Alsafadi, S. Alsalman, F. Paradisi “Extreme halophilic alcohol dehydrogenase mediated highly efficient syntheses of enantiopure aromatic alcohols” Organic and Biomolecular Chemistry 2017, 15, 9169-9175 (doi:10.1039/C7OB02299A)

M. L. Contente, F. Dall’Oglio, L. Tamborini, F. Molinari, F. Paradisi “Highly efficient oxidation of amines to aldehydes with flow-based biocatalysisChemCatChem, 2017, 9, 3805-4013 (doi:10.1002/cctc.201701147) (Front Cover)

A. Wester, M. Devocelle, E. A. Tallant, M. C. Chappell, P. E. Gallagher, F. Paradisi “Stabilization of Angiotensin-(1–7) by key substitution with a cyclic non-natural amino acidAmino Acids, 2017, 49,  1733-1742 (doi:10.1007/s00726-017-2471-9)

M. Planchestainer, M.L. Contente, J. Cassidy, F. Molinari, L. Tamborini, F. Paradisi “Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongataGreen Chemistry, 2017, 19, 372-375 (doi:10.1039/C6GC01780K)


2016 – 2013

M.L. Contente, M. Planchestainer, F. Molinari, L. Tamborini, F. Paradisi “Stereoelectronic effects in the reaction of aromatic substrates catalysed by Halomonas elongata transaminase and its mutantsOrganic and Biomolecular Chemistry 2016, 16, 9306-9311 (doi:10.1039/C6OB01629D)

B. Kutasy, F. Friedmacher, L. Pes, D. Coyle, T. Doi F. Paradisi, P. Puri “Antenatal Retinoic Acid Administration Increases Trophoblastic Retinol-Binding Protein Dependent Retinol Transport in the Nitrofen Model of Congenital Diaphragmatic HerniaPediatric Resaearch 2016, 76, 614-620

L. Cerioli, M. Planchestainer, J. Cassidy, D. Tessaro, F. Paradisi “Characterization of a novel amine transaminase from Halomonas elongataJournal of Molecular Catalysis B: Enzymatic 2015, 120, 141–150

H. Takahashi, B. Kutasy, L. Pes, F. Paradisi, P. Puri “Decidual β-carotene-15,15’-oxygenase-1 and 2 (BCMO1,2) expression is increased in nitrofen model of congenital diaphragmatic herniaPaediatric Surgery International 2015, 31, 37-43

K. Pandurangan, J. A. Kitchen, S. Blasco, F. Paradisi, T. Gunnlaugsson “Supramolecular pyridyl urea gels as soft matter with antibacterial properties against MRSA and/or E. coliChem Commun 2014, 50, 10819-10822

B. Kutasy, L. Pes, F. Friedmacher, F. Paradisi, P. Puri “Nitrofen increases total retinol levels in placenta during lung morphogenesis in the nitrofen model of congenital diaphragmatic hernia Paediatric Surgery International 2014, 30, 1017-1022

B. Kutasy, F. Friedmacher, L. Pes, F. Paradisi, P. Puri “Increased uptake of dietary retinoids at the maternal-fetal barrier in the nitrofen model of congenital diaphragmatic herniaJournal of Paediatric Surgery 2014, 49, 866-870

D. Alsafadi, F. Paradisi “Covalent immobilization of alcohol dehydrogenase (ADH2) from Haloferax volcanii: how to maximize activity and optimize performance of halophilic enzymesMolecular Biotechnology 2014, 56, 240-247

W. Streciwilk, J. Cassidy, F. Hackenberg, H. Müller-Bunz, F. Paradisi, M. Tacke “Synthesis, cytotoxic and antibacterial studies of p-benzyl-substituted NHC-silver(I) acetate compounds derived from 4,5-di-p-diisopropylphenyl- or 4,5-di-p-chlorophenyl-1H-imidazole” Journal of Organometallic Chemistry 2014, 749, 88-99

K. Robertson, C. Murphy, F. Paradisi “The Synthesis and Biological Testing of Bacilysin AnaloguesAmino Acids 2013, 45, 1157-1168

A. Liliensiek, J. Cassidy, G. Gucciardo, C. Whitely, F. Paradisi “Heterologous overexpression, purification and characterisation of an alcohol dehydrogenase (ADH2) from Halobacterium sp. NRC-1” Molecular Biotechnology 2013, 55, 143-149

D. Quaglia, M. Pori, P. Galletti, E. Emer, F. Paradisi and D. Giacomini “His-tagged Horse Liver Alcohol Dehydrogenase: Immobilization and application in the bio-based enantioselective synthesis of (S)-arylpropanols” Process Biochemistry 2013, 48, 810-818

E. O’Reilly, L. Pes, Y. Ortin, H. Müller-Bunz , F. Paradisi “Synthesis of a conformationally constrained δ-amino acid building block” Amino Acids 2013, 44, 511-518

D. Alsafadi, F. Paradisi “Effect of organic solvents on the activity and stability of halophilic alcohol dehydrogenase (ADH2) from Haloferax volcaniiExtremophiles 2013, 17, 115-122

F. Hackenberg, G. Lally, H. Müller-Bunz, F. Paradisi, D. Quaglia, W. Streciwilk, M. TackeSynthesis and biological evaluation of N-heterocyclic carbene-silver(I) acetate complexes derived from 4,5-ditolyl-imidazole” Inorganica Chimica Acta 2013, 395, 135-144

L. Timpson, A. Liliensiek, D. Alsafadi, M. A. Sharkey, S. Liddell, T. Allers, F. Paradisi “A comparison of two novel alcohol dehydrogenase enzymes (ADH1 and ADH2) from the extreme halophile Haloferax volcaniiApplied Microbiology and Biotechnology  2013, 97, 195-203em. 2010, 1020-1031

2012 – 2010


M. A. Sharkey, J. P. O’Gara, S. V. Gordon , F. Hackenberg, C. Healy, F. Paradisi, S. Patil, B. Schaible,  M. Tacke “Investigations into the Antibacterial Activity of the Silver-Based Antibiotic Drug Candidate SBC3” Antibiotics 2012, 1, 25-28

D. Quaglia, J. Irwin, F. Paradisi “Horse Liver Alcohol Dehydrogenase: new perspectives for an old enzyme”Molecular Biotechnology  2012, 52, 244-250

F. Hackenberg, G. Lally, H. Müller-Bunz, F. Paradisi, D. Quaglia, W. Streciwilk, M. Tacke Novel symmetrically p-benzyl-substituted 4,5-diaryl-imidazole N-heterocyclic carbene-silver(I) acetate complexes – synthesis and biological evaluation Journal of Organometallic Chemistry 2012, 717, 123-134

D. Balducci, P. A. Conway, G. Sapuppo, H. Müller-Bunz, F. Paradisi “Novel approach to the synthesis of aliphatic and aromatic alpha-keto acids” Tetrahedron 2012, 68, 7374-7379

E. Lestini, K. Robertson, C.D. Murphy, F. Paradisi “An alternative mild route to the synthesis of 4-methylenecyclohex-2-enone, a key moiety of the anticancer compounds ottelione A and B” Synthetic Communication 2012, 42,1864-1876 

F. Hackenberg, A. Deally, G. Lally, Sina Malenke,, H. Müller-Bunz, F. Paradisi, S. Patil, D. Quaglia,   M. Tacke “Novel non-symmetrically p-benzyl-substituted (benz)imidazole N-heterocyclic carbene-silver(I) acetate complexes – synthesis and biological evaluation” Int. Journal of Inorganic Chemistry 2012, vol. 2012, Article ID 121540, 13 pages.

L. Timpson, D. Alsafadi, C. Mac Donnchadha, S. Liddell, M. A. Sharkey, F. Paradisi “Characterization of alcohol dehydrogenase (ADH12) from Haloarcula marismortui, an extreme halophile from the Dead SeaExtremophiles 2012, 16, 57-66

S. Devereux , P. S. Shuttleworth, D. J. Macquarrie, and F. Paradisi “Isolation and Characterisation of Recovered Starch from Industrial Wastewater” Journal of Polymers and the Environment 2011, 19, 971-979

K. Pandurangan, K. D. Murnaghan, A. Walshe, H. Müller-Bunz, F. Paradisi and G. G. Morgan Design, Synthesis and Structure of Novel para-quinones and their Antibacterial Activity” Chemical Biology and Drug Design 2011,78, 787-799 

A. O’Sullivan,  D. Balducci, F. Paradisi,  K. Cashman, M. J. Gibney, L. Brennan Effects of supplementation with vitamin D3 on glucose production pathways in human subjects” Molecular Nutrition & Food Research 2011, 55, 1018–1025 

S. Patil, A. Deally, B. Gleeson, F. Hackenberg, H. Müller-Bunz, F. Paradisi, M. Tacke “Synthesis, Cytotoxicity and Antibacterial Studies of Novel Symmetrically and Non-Symmetrically p-Nitrobenzyl-Substituted N-Heterocyclic Carbene- Silver(I) Acetate Complexes” Journal of Inorganic and General Chemistry 2011, 637, 386–396 

S. Patil, A. Deally, B. Gleeson, H. Müller-Bunz, F. Paradisi, M. Tacke.”Novel Benzyl-Substituted N-Heterocyclic Carbene–Silver Acetate Complexes: Synthesis, Cytotoxicity and Antibacterial Studies” Metallomics 2011, 3, 74-88 

S. Patil, K. Dietrich, Deally, B. Gleeson, H. Müller-Bunz, F. Paradisi, M. Tacke “Synthesis, Cytotoxicity and Antibacterial Studies of Novel Symmetrically and Non-Symmetrically 4-(Methoxycarbonyl)benzyl-Substituted N-Heterocyclic Carbene-Silver Acetate Complexes” Helvetica Chimica Acta 2010, 93, 2347-2364 

D. O. Frimannsson, M. Grossi, J. Murtagh, F. Paradisi and D. F. O´Shea “Light Induced Anti-microbial Properties of a Brominated BF2 – Chelated Tetraarylazadipyrromethene Photosensitizer” J. Med. Chem. 2010, 53, 7337-7343 

S. Patil, J. Claffey, B. Gleeson, H. Müller-Bunz, F. Paradisi, M. Tacke “Synthesis, Cytotoxicity and Antibacterial Studies of Symmetrically and Non-Symmetrically Benzyl- or p- Cyanobenzyl-Substituted N-Heterocyclic Carbene-Silver Complexes” Applied. Organometallic Chemistry 2010, 24, 781–793

K. Pandurangan, S. Gallagher, G. G. Morgan, H. Müller-Bunz, F. Paradisi “Structure and Anti-Microbial Activity of the Silver(I) Complex of 2-Aminophenoxazine-3-one” Metallomics 2010, 2, 530-534 (Front cover)

E. O’Reilly, D. Balducci, F. Paradisi A stereoselective synthesis of α-deuterium labelled (S)-α-amino acids” Aminoacids 2010, 39, 849-858

E. O’Reilly, L. Pes, F. Paradisi “From amines to diketopiperazines: a one-pot approach” Tetrahedron Lett. 2010,51, 1696-1697

S. Patil, J. Claffey, A. Deally, M. Hogan, B. Gleeson, L. M. Menéndez Méndez, H. Müller-Bunz, F. Paradisi, D. Wallis, M. Tacke “Synthesis, Cytotoxicity and Antibacterial Studies of p-Methoxybenzyl-Substituted and Benzyl-Substituted N-Heterocyclic Carbene-Silver Complexes” Eur. J. Inorg. Chem. 2010, 1020-1031

S. Moran, K. Robertson, F. Paradisi, D. Rai, C. Murphy Production of lipopeptides in Bacillus sp. CS93 isolated from Pozol” FEMS Letters 2010, 304, 69-73P

2009 -2007


A. Conway, K. Devine, F. Paradisi “A simple and efficient method for the synthesis of Erlenmeyer azlactonesTetrahedron 2009, 65, 2935-2938

E.O’Reilly, E. Lestini, D. Balducci, F. Paradisi One-step diketopiperazine synthesis using phase transfer catalysis” Tetrahedron Lett. 2009, 50, 1748-1750

B. Gleeson, J. Claffey, D. Ertler, M. Hogan, H. Müller-Bunz, F. Paradisi, D. Wallis, M. Tacke “Novel organotin antibacterial and anticancer drugs  Polyhedron 2008, 27, 3619-3624

F. Paradisi, P.A. Conway, A. Maguire, P. C. Engel Engineered dehydrogenase biocatalysts for non-natural amino acids: efficient isolation of the D-enantiomer from racemic mixtures Organic and Biomolecular Chemistry 2008, 6, 3611-3615

D. Giacomini, P. Galletti, A. Quintavalla, G. Gucciardo, F. Paradisi Highly Efficient Asymmetric Reduction of Arylpropionic-aldehydes by Horse Liver Alcohol-Dehydrogenase Through Dynamic Kinetic Resolution” Chem.Commun. 2007, 4038-4040 (Highlighted as a HOT TOPIC)

N. Nakazawa, S. Montedonico, H. Takayasu, F. Paradisi, Prem Puri “Disturbance of retinol transportation causes Nitrofen induced hypoplastic lung” J. Pediatr. Surg., 2007, 42, 345-349 

Previous Work  

F. Paradisi, S. Collins, A. R. Maguire, P. C. Engel “Phenylalanine dehydrogenase mutants: Efficient biocatalysts for synthesis of non-natural phenylalanine derivatives” J. Biotechnol., 2007,128, 408-411 

E. Faulkner, M. Barret, S. Okor, F. Paradisi, P. C. Engel, B. Glennon “The use of fed batch cultivation for achieving high cell densities for the pilot scale production of a recombinant protein (Phenylalanine dehydrogenase) in Escherichia coli” Biotechnology Progress 2006, 22, 889-897

G. Cainelli, P. Engel, P.Galletti, D. Giacomini, A. Gualandi, F. Paradisi Engineered Phenylalanine Dehydrogenase in Organic Solvents: Homogeneous and Biphasic Enzymatic Reaction Organic and Biomolecular Chemistry,2005, 3, 4316–4320

F. Paradisi, R. Woolfson, K.F. Geoghegan, P.C. Engel “Identification of the Residue Responsible for Catalysing Regeneration of Activity in the Inactive Glutamate Dehydrogenase Mutant D165N” FEBS letters, 2005, 579, 2830-2832

F. Paradisi, J.L.E. Dean, K.F. Geoghegan, P.C. Engel “Spontaneous chemical reversion of an active site mutation: Deamidation of an asparagine residue replacing the catalytic aspartic acid of glutamate dehydrogenase” Biochemistry, 2005, 44, 3636-3643

P. Busca, F. Paradisi, E. Moynihan, A. R. Maguire, P. C. Engel “Enantioselective Synthesis of Non-natural Amino Acids using Phenylalanine Dehydrogenases Modified by Site-directed Mutagenesis Organic and Biomolecular Chemistry 2004, 2, 2684 – 2691

N. E. Batoux, F. Paradisi, P. C. Engel, M. E. Migaud “Novel Nicotinamide Adenine Dinucleotide analogues as selective inhibitors of  NAD+-dependent enzymes  Tetrahedron 2004, 60, 6609-6617

A. Arcelli, F. Paradisi, G. Porzi, S. Rinaldi, S. Sandri “Acid Hydrolysis of the Ether Bond Assisted by the Neighbouring Amide Group: Effects Induced by Salts and by Structural Changes. Part 6” Journal of Chemical Research (Synopses) 2002, 5, 501-518

F. Paradisi, F. Piccinelli, G. Porzi, S. Sandri “Enantioselective Synthesis of 2,6-diaminopimelic acid derivatives. Part 3 Tetrahedron: Asymmetry 2002, 13, 497-502

F. Paradisi, G. Porzi, S. Sandri “A new stereocontrolled synthesis of uncommon tripeptides derived from (2,6)-diaminopimelic acid (2,6-DAP)” Tetrahedron: Asymmetry 2001, 12, 3319-3324

G. Cainelli, D. Giacomini, P. Galletti, P. Orioli, F. Paradisi “Diastereofacial Selectivity of O-protected-a – Hydroxy Aldehydes: Temperature and Solvent effect Eur. J. Org. Chem. 2000, 3619-3626

F. Paradisi, G. Porzi, S. Rinaldi, S. Sandri “Stereoselective synthesis of a,a’-diaminodicarboxylic acids. Part 2” Tetrahedron: Asymmetry 2000, 11, 4617-4622

F. Paradisi, G. Porzi, S. Rinaldi, S. Sandri “A simple asymmetric synthesis of (+)- and (-) -2,6-diaminopimelic acids Tetrahedron: Asymmetry 2000, 11, 1259-1262

P. Di Felice, M. Maestri, F. Paradisi, G. Porzi, S. Sandri “Highly stereocontrolled boron-mediated synthesis of β-hydroxy-α-aminoacids and dipeptides. Part 2” Tetrahedron: Asymmetry 1999, 10, 4709-4714.